Title
Effect of MR Distortion on Targeting for Deep-Brain Stimulation
Abstract
Deep-brain stimulation (DBS) surgery involves placing electrodes within specific deep-brain target nuclei. Surgeons employ MR imaging for preoperative selection of targets and computed tomography (CT) imaging for designing stereotactic frames used for intraoperative placement of electrodes at the targets. MR distortion may contribute to target-selection error in the MR scan and also to MR-CT registration error, each of which contributes to error in electrode placement. In this paper, we analyze the error contributed by the MR distortion to the total DBS targeting error. Distortion in conventional MR scans, both T1 and T2 weighted, were analyzed for six bilateral DBS patients in the typical areas of brain using typical scans on a 3-T clinical scanner. Mean targeting error due to MR distortion in T2 was found to be 0.07 +/- 0.025 mm with a maximum of 0.13 mm over 12 targets; error in the T1 images was smaller by 4%.
Year
DOI
Venue
2010
10.1109/TBME.2010.2043675
Biomedical Engineering, IEEE Transactions
Keywords
Field
DocType
bioelectric phenomena,biomedical MRI,biomedical electrodes,brain,computerised tomography,image registration,medical image processing,surgery,MR distortion,MR imaging,MR-CT registration error,computed tomography,deep brain stimulation surgery,electrodes,stereotactic frames,target selection error,Deep brain,MR distortion,error,registration,targeting
Biomedical engineering,Deep brain stimulation,Medical imaging,Imaging phantom,Image processing,Scanner,Distortion,Medicine,Image registration,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
57
7
0018-9294
Citations 
PageRank 
References 
3
0.54
4
Authors
4
Name
Order
Citations
PageRank
Ramya Balachandran110216.70
E. Brian Welch24516.66
Benoit M. Dawant3611119.44
J. Michael Fitzpatrick4598133.90