Title
Remarks on the invalidation of biological models using monotone systems theory
Abstract
Cooperative systems, and more generally systems with sign-definite interactions between variables, are an important class of models in several domains of applications, and in particular in molecular biology. The goal of this paper is to present techniques for finding out what type of solutions are compatible with a given sign pattern of interactions among state/input variables, once the input behaviour is also known. By “type” of solutions we mean the sequence of upwards or downwards segments that variables can exhibit (essentially sign-patterns derivatives of variables) once input profiles are also specified.
Year
DOI
Venue
2012
10.1109/CDC.2012.6426795
Decision and Control
Keywords
Field
DocType
biology,molecular biophysics,system theory,biological model invalidation,cooperative system,molecular biology,monotone systems theory,sign-definite interaction
Systems theory,Control theory,Computer science,Molecular biophysics,Monotone polygon
Conference
ISSN
ISBN
Citations 
0743-1546 E-ISBN : 978-1-4673-2064-1
978-1-4673-2064-1
7
PageRank 
References 
Authors
0.58
2
2
Name
Order
Citations
PageRank
David Angeli11264153.03
Eduardo D. Sontag23134781.88