Name
Title | ||
|---|---|---|
Semi-automatic classification of lesion patterns in patients with clinically isolated syndrome |
Abstract | ||
|---|---|---|
Multiple sclerosis (MS) is neuro-degenerative disease of the Central Nervous System characterized by the loss of myelin. A Clinically Isolated Syndrome (CIS) is a first neurological episode caused by inflammation/demyelination in the central nervous system which may lead to MS. Better understanding of the disease at its onset will lead to a better discovery of pathogenic mechanisms, allowing suitable therapies at an early stage. We propose an automatic segmentation algorithm for two different contrast agents, used within a framework for early characterization of CIS patients according to lesion patterns, and more specifically according to the nature of the inflammatory patterns of these lesions. We expect that the proposed framework can infer new prospective figures from the earliest imaging signs of MS since it can provide a classification of different types of lesions across patients. The lesion detection algorithm based on intensity normalization and subtraction of the used MRI data is a pivotal step, since it avoids the time-demanding task of manual delineation. |
Year | DOI | Venue |
|---|---|---|
2013 | 10.1109/ISBI.2013.6556671 | Biomedical Imaging |
Keywords | Field | DocType |
biomedical MRI,diseases,feature extraction,image classification,image segmentation,medical image processing,neurophysiology,CIS patients,MRI data,automatic segmentation algorithm,central nervous system,clinically isolated syndrome,contrast agents,feature extraction,inflammation-demyelination,lesion pattern semiautomatic classification,manual delineation,myelin loss,neurodegenerative disease,pathogenic mechanism,pivotal step,time-demanding task,MS,Segmentation,USPIO,longitudinal Study | Central nervous system,Computer vision,Disease,Neurophysiology,Lesion,Multiple sclerosis,Artificial intelligence,Clinically isolated syndrome,Medicine,Subtraction,Pathology,Myelin | Conference |
ISSN | ISBN | Citations |
1945-7928 | 978-1-4673-6456-0 | 0 |
PageRank | References | Authors |
0.34 | 3 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Crimi, A. | 1 | 0 | 0.34 |
| Commowick, O. | 2 | 10 | 0.91 |
| Jean-Christophe Ferré | 3 | 18 | 6.07 |
| Maarouf, A. | 4 | 1 | 0.69 |