Title
Experimental comparison of classification methods for key kinase identification for neurite elongation.
Abstract
Kinases in a developing neuron play important roles in elongating a neurite with their complex interactions. To elucidate the effect of each kinase on neurite elongation and regeneration from a small set of experiments, we applied machine learning methods to synthetic datasets based on a biologically feasible model. The result showed the ridged partial least squares (RPLS) algorithm performed better than other standard algorithms such as naive Bayes classifier, support vector machines and random forest classification. This suggests the effectiveness of dimension reduction done in RPLS.
Year
DOI
Venue
2013
10.1109/EMBC.2013.6610301
EMBC
Keywords
Field
DocType
biomechanics,biologically feasible model,naive bayes classifier,ridged partial least square algorithm,neurophysiology,machine learning methods,kinase identification,learning (artificial intelligence),synthetic datasets,rpls algorithm,enzymes,biochemistry,molecular biophysics,least squares approximations,bayes methods,complex interactions,neurite elongation,random forest classification,medical computing,elongation,support vector machines,classification methods,vectors,learning artificial intelligence,chemicals,vegetation
Standard algorithms,Dimensionality reduction,Computer science,Partial least squares regression,Artificial intelligence,Computational biology,Neurite,Random forest,Computer vision,Naive Bayes classifier,Least squares support vector machine,Support vector machine,Machine learning
Conference
Volume
ISSN
Citations 
2013
1557-170X
0
PageRank 
References 
Authors
0.34
2
6
Name
Order
Citations
PageRank
Yuji Yoshida100.34
Kei Majima200.34
Tatsuya Yamada300.34
Yuki Maruno400.34
Yuichi Sakumura500.34
K. Ikeda624155.17