Name
Title | ||
|---|---|---|
Band specific changes in thalamocortical synchrony in field potentials after cardiac arrest induced global hypoxia. |
Abstract | ||
|---|---|---|
Cardiac Arrest (CA) leads to a global hypoxic-ischemic injury in the brain leading to a poor neurological outcome. Understanding the mechanisms of functional disruption in various regions of the brain may be essential for the development of improved diagnostic and therapeutic solutions. Using controlled laboratory experiment with animal models of CA, our primary focus here is on understanding the functional changes in the thalamus and the cortex, associated with the injury and acute recovery upon resuscitation. Specifically, to study the changes in thalamocortical synchrony through these periods, we acquired local field potentials (LFPs) from the ventroposterior lateral (VPL) nucleus of the thalamus and the forelimb somatosensory cortex (S1FL) in rats after asphyxial CA. Band-specific relative Hilbert phases were used to analyze synchrony between the LFPs. We observed that the CA induced global ischemia changes the local phase-relationships by introducing a phase-lag in both the thalamus and the cortex, while the synchrony between the two regions is nearly completely lost after CA. |
Year | DOI | Venue |
|---|---|---|
2013 | 10.1109/EMBC.2013.6611197 | EMBC |
Keywords | Field | DocType |
phase-lag,ventroposterior lateral nucleus,acute recovery,asphyxial ca,cardiology,bioelectric potentials,diseases,global hypoxic-ischemic injury,band-specific relative hilbert phase,brain region,neurophysiology,resuscitation,electroencephalography,s1fl,animal model,local phase-relationship,thalamus,injuries,forelimb somatosensory cortex,lfp,band specific changes,thalamocortical synchrony,diagnostic development,neurological outcome,patient diagnosis,local field potential,patient treatment,functional disruption mechanism,cardiac arrest,therapeutic solution development,electric potential | Thalamus,Cortex (botany),Neuroscience,Nucleus,Electroencephalography Phase Synchronization,Local field potential,Somatosensory system,Forelimb,Medicine,Electroencephalography | Conference |
Volume | ISSN | Citations |
2013 | 1557-170X | 0 |
PageRank | References | Authors |
0.34 | 1 | 7 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Anil Maybhate | 1 | 2 | 1.70 |
| Cheng Chen | 2 | 3 | 0.76 |
| Yama Akbari | 3 | 0 | 0.68 |
| David L. Sherman | 4 | 32 | 4.38 |
| Kaiquan Shen | 5 | 0 | 0.34 |
| Xiaofeng Jia | 6 | 44 | 8.75 |
| Nitish V Thakor | 7 | 38 | 9.68 |