Title
3-D Active Meshes: Fast Discrete Deformable Models for Cell Tracking in 3-D Time-Lapse Microscopy
Abstract
Variational deformable models have proven over the past decades a high efficiency for segmentation and tracking in 2-D sequences. Yet, their application to 3-D time-lapse images has been hampered by discretization issues, heavy computational loads and lack of proper user visualization and interaction, limiting their use for routine analysis of large data-sets. We propose here to address these limitations by reformulating the problem entirely in the discrete domain using 3-D active meshes, which express a surface as a discrete triangular mesh, and minimize the energy functional accordingly. By performing computations in the discrete domain, computational costs are drastically reduced, whilst the mesh formalism allows to benefit from real-time 3-D rendering and other GPU-based optimizations. Performance evaluations on both simulated and real biological data sets show that this novel framework outperforms current state-of-the-art methods, constituting a light and fast alternative to traditional variational models for segmentation and tracking applications.
Year
DOI
Venue
2011
10.1109/TIP.2010.2099125
IEEE Transactions on Image Processing
Keywords
Field
DocType
biological techniques,biology computing,cell motility,image segmentation,image sequences,mesh generation,minimisation,optical microscopy,physiological models,rendering (computer graphics),2D sequence segmentation,2D sequence tracking,3D active meshes,3D time lapse microscopy,GPU-based optimizations,cell tracking,discrete triangular mesh,energy functional minimization,fast discrete deformable models,real-time 3D rendering,3-D active meshes,Biological image sequence,cell tracking,deformable models
Discretization,Computer vision,Polygon mesh,Computer science,Image segmentation,Solid modeling,Artificial intelligence,Rendering (computer graphics),Mesh generation,Triangle mesh,Computational complexity theory
Journal
Volume
Issue
ISSN
20
7
1057-7149
Citations 
PageRank 
References 
44
2.32
47
Authors
4
Name
Order
Citations
PageRank
A. Dufour1533.57
Thibeaux, R.2442.32
Elisabeth Labruyère316614.20
Nancy Guillen416915.25