Title
Enhanced reference guided assembly
Abstract
Next Generation Sequencing has totally changed genomics: we are able to produce huge amounts of data at an incredible low cost if compared to Sanger sequencing. Despite this some old problems have become even more difficult, de-novo assembly being on top of this list. In this paper we propose a novel method that aims at improving de-novo assembly in presence of a closely related reference. The idea is to combine de-novo assembly and reference guided assembly in order to obtain an enhanced assembly.
Year
DOI
Venue
2010
10.1109/BIBM.2010.5706540
Bioinformatics and Biomedicine
Keywords
Field
DocType
DNA,genomics,molecular biophysics,de novo assembly,enhanced reference guided assembly,genomics,next generation sequencing,De-Novo Assembly,NGS,reference assembly
Computer science,Genomics,DNA sequencing,Bioinformatics,Sanger sequencing,Artificial neural network,Sequence assembly
Conference
ISSN
ISBN
Citations 
2156-1125
978-1-4244-8307-5
2
PageRank 
References 
Authors
0.43
6
3
Name
Order
Citations
PageRank
Federica Cattonaro130.79
Alberto Policriti278574.35
Francesco Vezzi3796.03