Name
Abstract | ||
|---|---|---|
Non-invasive measures of the fetal ECG provide quantitative information on pacemaking rate, propagation times and velocities during normal sinus rhythm. One dimensional partial differential equation models of propagation that reproduce fetal normal sinus rhythm in hearts from 16-40 weeks gestational age were constructed Lengths were obtained from magnetic resonance imaging data, intercellular coupling informed by ECG timings, and cell excitation described by modified models for adult human cardiac cells. Spatially uniform progressive reduction of the L-type calcium conductance slowed the rate, and led to atrioventricular conduction blocks. Self terminating and persistent re-entry with a period of 240 - 300ms could be produced within a 1-D ring ventricular tissue model. The preliminary 1-D family of models quantitatively reproduces the observed timings of fECG intervals from 16-40 WGA, and predicts the characteristics of development of fetal A V block, and self terminating ventricular tachycardia. |
Year | Venue | Keywords |
|---|---|---|
2013 | CinC | bioelectric phenomena,electrocardiography,medical disorders,obstetrics,partial differential equations,physiological models,1d partial differential equation,1d ring ventricular tissue model,ecg timing,l-type calcium conductance,adult human cardiac cell modified models,age 0.307 yr to 0.767 yr,atrioventricular conduction blocks,cell excitation,computational modeling,fetal av block,fetal ecg noninvasive measures,human fetal arrhythmia,human fetal normal sinus rhythm,intercellular coupling,magnetic resonance imaging data,pacemaking rate,persistent reentry,propagation models,propagation time,propagation velocity,self terminating reentry,self terminating ventricular tachycardia,spatially uniform progressive reduction,time 240 ms to 300 ms |
Field | DocType | Volume |
Fetus,Internal medicine,Cardiology,Normal Sinus Rhythm,Ventricular tachycardia,Electrocardiography,Tissue Model,Medicine,Gestational age,Magnetic resonance imaging | Conference | 40 |
ISSN | ISBN | Citations |
2325-8861 | 978-1-4799-0884-4 | 0 |
PageRank | References | Authors |
0.34 | 0 | 8 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Alan P. Benson | 1 | 4 | 5.14 |
| adam bleakley | 2 | 0 | 0.34 |
| sam hodgson | 3 | 0 | 0.34 |
| Arun V. Holden | 4 | 52 | 20.71 |
| nikki pelech | 5 | 0 | 0.34 |
| ebrahim palkhi | 6 | 0 | 0.34 |
| Eleftheria Pervolaraki | 7 | 1 | 1.42 |
| catherine whitfield | 8 | 0 | 0.34 |