Title
Automatic Parameterization Strategy for Cardiac Electrophysiology Simulations.
Abstract
Driven by recent advances in medical imaging, image segmentation and numerical techniques, computer models of ventricular electrophysiology account for increasingly finer levels of anatomical and biophysical detail. However, considering the large number of model parameters involved parameterization poses a major challenge. A minimum requirement in combined experimental and modeling studies is to achieve good agreement in activation and repolarization sequences between model and experiment or patient data. In this study, we propose basic techniques which aid in determining bidomain parameters to match activation sequences. An iterative parameterization algorithm is implemented which determines appropriate bulk conductivities which yield prescribed velocities. In addition, a method is proposed for splitting the computed bulk conductivities into individual bidomain conductivities by prescribing anisotropy ratios.
Year
Venue
Keywords
2013
CinC
bulk conductivity computation,cardiology,ventricular electrophysiology,bioelectric potentials,cardiac electrophysiology simulations,parameter estimation,electrical conductivity,medical image segmentation,computer models,automatic parameterization strategy,numerical techniques,repolarization sequences,anisotropy ratios,activation sequences,patient data,bidomain conductivities,iterative methods,iterative parameterization algorithm
Field
DocType
Volume
Anisotropy,Parametrization,Medical imaging,Iterative method,Simulation,Computer science,Algorithm,Cardiac electrophysiology,Image segmentation,Estimation theory
Conference
40
ISSN
ISBN
Citations 
2325-8861
978-1-4799-0884-4
3
PageRank 
References 
Authors
0.44
1
5
Name
Order
Citations
PageRank
Caroline Mendonça Costa1104.59
Elena Hoetzl230.44
Bernardo Martins Rocha330.44
Anton J. Prassl4233.88
G Plank520133.05