Title
T-wave alternans predicts ICD discharge in MADIT II patients with elevated resting heart rate
Abstract
The identification of MADIT II patients who might benefit the most from implantable cardioverter defibrillator (ICD) therapy remains a clinical challenge. In this work we measure T-wave alternans (TWA) using the multilead Laplacian likelihood ratio method (mLLR) in MADIT II patients, and we evaluate its ability to predict ventricular tachycardia or ventricular fibrillation events requiring an ICD shock and to predict sudden cardiac death (SCD). Our results indicate that the average TWA measured between 80 and 90 beats/min in resting ECGs is associated with future ICD therapy in MADIT II patients with elevated resting heart rate.
Year
Venue
Keywords
2013
CinC
laplace equations,defibrillators,diseases,electrocardiography,prosthetics,statistical analysis,icd discharge prediction,icd shock,icd therapy,madit ii patients,scd prediction,t-wave alternans measurement,average twa measurement,implantable cardioverter defibrillator,mllr method,multilead laplacian likelihood ratio method,resting ecgs,resting heart rate elevation,sudden cardiac death prediction,ventricular fibrillation events prediction,ventricular tachycardia prediction
Field
DocType
Volume
RESTING HEART RATE,Ventricular fibrillation,Internal medicine,Cardiology,Sudden cardiac death,Ventricular tachycardia,T wave alternans,Electrocardiography,Medicine,Statistical analysis,Implantable cardioverter-defibrillator
Conference
40
ISSN
ISBN
Citations 
2325-8861
978-1-4799-0884-4
0
PageRank 
References 
Authors
0.34
1
7
Name
Order
Citations
PageRank
Violeta Monasterio1173.73
Juan Pablo Martínez2394.21
scott mcnitt300.68
P Laguna425574.15
Moss, J.582.97
Wojciech Zareba6133.58
Jean-Philippe Couderc7436.67