Paper Info
Title
Modeling environmental disturbances with the chemical master equation
Abstract
In this paper we consider the problem of representing a biological system and its environment using a stochastic modeling framework. We first introduce a decomposition of the global chemical reaction system into two systems: a system of interest and its environment. We then present and derive a decomposition of the chemical master equation to achieve a representation describing the dynamics of the system of interest, perturbed by an environmental disturbance. We use this decomposition to model examples of two types of environmental disturbances: the disturbance a system experiences through loading effects from limited resources and the disturbance a system experiences when perturbed by an antibiotic that modifies transcription or translation rates.
Year
DOI
Venue
2013
10.1109/CDC.2013.6760076
Decision and Control
Keywords
DocType
ISSN
biochemistry,chemical reactions,master equation,stochastic processes,biological system,chemical master equation,environmental disturbance,global chemical reaction system,stochastic modeling framework
Conference
0743-1546
ISBN
Citations 
PageRank 
978-1-4673-5714-2
0
0.34
References 
Authors
4
3
Name
Order
Citations
PageRank
Enoch Yeung1189.21
James L. Beck26813.03
Richard M. Murray3123221223.70