Title
Waveform processing for protein multi-alignment by mapping location, structure and property function attributes
Abstract
We propose a pairwise protein structure alignment approach based on a joint similarity measure of multiple protein attributes. We map information on a protein's sequence location, structure and characteristic properties onto a highly-localized three-dimensional Gaussian waveform. By allowing the waveform to undergo unique transformations in the time-frequency plane, we allocate distinct parameters to represent the different attributes. Protein matching by expanding the mapped waveforms using appropriately designed basis waveform functions provides a similarity measure to encompass the multiple attributes. Simulations using data from a database demonstrate the performance of the joint alignment approach to infer relationships between proteins.
Year
DOI
Venue
2013
10.1109/ACSSC.2013.6810270
Pacific Grove, CA
Keywords
Field
DocType
bioinformatics,pattern matching,proteins,time-frequency analysis,basis waveform functions,highly-localized three-dimensional Gaussian waveform,joint alignment approach,joint similarity measure,multiple protein attributes,pairwise protein structure alignment approach,property function attributes,protein matching,protein multialignment,protein sequence location mapping,time-frequency plane,waveform processing
Data mining,Similarity measure,Computer science,Matrix (mathematics),Artificial intelligence,Protein structure,Pairwise comparison,Mathematical optimization,Pattern recognition,Protein engineering,Waveform,Gaussian,Time–frequency analysis
Conference
ISSN
ISBN
Citations 
1058-6393
978-1-4799-2388-5
0
PageRank 
References 
Authors
0.34
5
3
Name
Order
Citations
PageRank
Brian O'Donnell101.01
Alexander Maurer200.34
Antonia Papandreou-Suppappola323429.88