Title | ||
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Tissue block MRI for slice orientation-independent registration of digital histology images to ex vivo MRI of the prostate |
Abstract | ||
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We present a method for the registration of whole-mount digital histology images to ex vivo MR images of the prostate that relaxes the requirement for control over specimen slicing orientation. The approach uses extrinsic fiducials visible on histology and MRI, as well as block MR images of tissue slices after coarse sectioning, to support a two-stage registration approach: (1) registration of digital histology images to block MR images, and (2) registration of block MR images to whole-specimen ex vivo MR images. This work presents a preliminary quantitative validation on 4 clinical prostate specimens, yielding target registration errors of 0.6 mm and 0.5 mm, respectively, for the registration stages, measured using intrinsic fiducials. |
Year | DOI | Venue |
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2011 | 10.1109/ISBI.2011.5872470 | Chicago, IL |
Keywords | Field | DocType |
biological organs,biological tissues,biomedical MRI,biomedical optical imaging,image registration,medical image processing,optical microscopy,block MR image registration,coarse sectioning,digital histology images,ex vivo prostate MRI,extrinsic fiducials,slice orientation independent registration,specimen slicing orientation,tissue block MRI,tissue slices,two stage registration approach,whole mount digital histology image registration,histopathology,imaging,prostate,registration | Nuclear medicine,Ex vivo,Computer vision,Fiducial marker,Computer science,Artificial intelligence,Prostate,Radiology,Histology,Image registration,Magnetic resonance imaging | Conference |
ISSN | ISBN | Citations |
1945-7928 E-ISBN : 978-1-4244-4128-0 | 978-1-4244-4128-0 | 2 |
PageRank | References | Authors |
0.42 | 3 | 4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Eli Gibson | 1 | 188 | 23.91 |
Crukley, C. | 2 | 2 | 0.42 |
Jose A Gomez | 3 | 43 | 7.53 |
Madeleine Moussa | 4 | 27 | 8.83 |