Title
Transfer learning of tissue photon interaction in optical coherence tomography towardsin vivo histology of the oral mucosa
Abstract
Oral cancer evolves from different premalignant conditions and the key to save lives is through diagnosis of early symptoms. The conventional practice of post biopsy histopathology reporting is dependent on specificity of sampling site and optical coherence tomography (OCT) imaging is clinically used for guidance. Clinicians infer the tissue constitution by interpreting intensity images and are challenged by inter-and intra-observer variability. In this paper we propose transfer learning of tissue specific photon interaction statistical physics in swept-source OCT for characterizing the oral mucosa with the aim of reducing this reporting variability. The source task models statistical physics of ballistic and near-ballistic photons and its intensity attenuation and target task learns the parameters obtained by solving the source task to identify co-located heterogeneity of tissues. Performance is compared with conventional histopathology of healthy, premalignant and malignant oral lesions supporting its use towards in vivo histology of the oral mucosa for pre-biopsy screening.
Year
DOI
Venue
2014
10.1109/ISBI.2014.6868137
Biomedical Imaging
Keywords
Field
DocType
bio-optics,biomedical optical imaging,cancer,image sampling,medical image processing,optical tomography,statistical analysis,tumours,ballistic photons,biopsy histopathology,early symptom diagnosis,histopathology,in vivo histology,intensity attenuation,malignant oral lesions,near-ballistic photons,optical coherence tomography,oral cancer,oral mucosa,prebiopsy screening,premalignant conditions,premalignant oral lesions,sampling site,source task models statistical physics,swept-source OCT,tissue constitution,tissue photon interaction,transfer learning,Optical coherence tomography,in vivo histology,oral cancer,tissue characterization,transfer learning
Optical coherence tomography,Computer science,Histopathology,Biopsy,Tomography,In vivo,Oral mucosa,Histology,Pathology,Carcinoma
Conference
ISSN
Citations 
PageRank 
1945-7928
2
0.62
References 
Authors
0
4
Name
Order
Citations
PageRank
Sheet, D.120.62
Subhash Banerjee271.77
Karri, S.P.K.3374.70
Bag, S.4191.86