Title
Modeling the leech heartbeat elemental oscillator II. Exploring the parameter space
Abstract
In the previous paper, we described a model of the elemental heartbeat oscillator in the leech. Here, the parameters of our model are explored around the baseline canonical model. The maximal conductances of the currents and the reversal potential of the leak current are varied to reveal the effects of individual currents and the interaction between synaptic and intrinsic currents in the model. The model produces two distinct modes of oscillation as the parameters are varied, S-mode and G-mode. These two modes are defined, their origin is identified, and the parameter space is mapped into S-mode and G-mode oscillation and no oscillation. Finally, we will make predictions for how the period can be modulated in heart interneurons.
Year
DOI
Venue
1995
10.1007/BF00961436
Journal of Computational Neuroscience
Keywords
Field
DocType
Parameter Space,Leak Current,Reversal Potential,Distinct Mode,Maximal Conductance
Heartbeat,Oscillation,Reversal potential,Control theory,Leech,Canonical model,Parameter space,Physics
Journal
Volume
Issue
ISSN
2
3
0929-5313
Citations 
PageRank 
References 
7
4.70
3
Authors
3
Name
Order
Citations
PageRank
Øystein H. Olsen1229.81
Farzan Nadim26820.17
Ronald L. Calabrese39024.40