Title
Proton-density-weighted spinal fMRI with sensorimotor stimulation at 0.2 T.
Abstract
Proton-density-weighted fMRI at low field (0.2 T) was carried out in the cervical spinal cord of healthy volunteers in this study to examine the feasibility of detecting proton density alteration accompanying activation in the spinal cord. Subjects were asked to grip both hands simultaneously, providing sensorimotor simulation for spinal fMRI. Over 70% subjects recruited had activation localized at C6–C7 spinal levels with discrete activation detected in both the anterior and posterior horns of the cervical spinal cord, and the average fractional signal change was 4.06%. The 0.2 T low magnetic field and the 24 ms short TE used in this study diminished the BOLD effect to a negligible level, thus the observed signal change was believed to be mainly attributable to proton density increase during neuronal stimulation. Our results suggested the existence of task-driven proton density change in the cervical spinal cord.
Year
DOI
Venue
2006
10.1016/j.neuroimage.2005.08.011
NeuroImage
Keywords
Field
DocType
MRI,fMRI,BOLD,SEEP,Proton density,Sensorimotor and spinal cord
Spinal cord,Neuroscience,Proton density,Psychology,Spinal fMRI,Stimulation
Journal
Volume
Issue
ISSN
29
3
1053-8119
Citations 
PageRank 
References 
8
0.85
1
Authors
7
Name
Order
Citations
PageRank
Man Cheuk Ng180.85
Kelvin K. Wong280.85
Geng Li380.85
Song Lai480.85
Edward S. Yang580.85
Yong Hu619738.46
Keith D. Luk780.85