Title | ||
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Cortical abnormalities in bipolar disorder investigated with MRI and voxel-based morphometry. |
Abstract | ||
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Bipolar disorder (BD) has been associated with abnormalities of brain structure. Specifically, in vivo volumetric MRI and/or post mortem studies of BD have reported abnormalities of gray matter (GM) volume in the medial prefrontal cortex (PFC), amygdala, hippocampal subiculum and ventral striatum. These structures share anatomical connections with each other and form part of a “visceromotor” network modulating emotional behavior. Areas of the lateral orbital, superior temporal and posterior cingulate cortices project to this network, but morphometric abnormalities in these areas have not been established in BD. The current study assessed tissue volumes within these areas in BD using MRI and voxel-based morphometry (VBM). |
Year | DOI | Venue |
---|---|---|
2006 | 10.1016/j.neuroimage.2005.09.029 | NeuroImage |
Keywords | Field | DocType |
Morphometry,Bipolar depression,Magnetic resonance imaging | Developmental psychology,Ventral striatum,White matter,Glucocorticoid secretion,Prefrontal cortex,Psychology,Voxel-based morphometry,Posterior cingulate,Retrosplenial cortex,Superior temporal gyrus | Journal |
Volume | Issue | ISSN |
30 | 2 | 1053-8119 |
Citations | PageRank | References |
4 | 0.89 | 6 |
Authors | ||
10 |
Name | Order | Citations | PageRank |
---|---|---|---|
Allison C Nugent | 1 | 12 | 2.15 |
Michael P Milham | 2 | 884 | 48.19 |
Earle E Bain | 3 | 4 | 0.89 |
Linda Mah | 4 | 4 | 0.89 |
Dara M Cannon | 5 | 4 | 1.23 |
Sean Marrett | 6 | 16 | 2.19 |
Carlos A. Zarate | 7 | 8 | 1.94 |
Daniel S Pine | 8 | 108 | 12.74 |
Joseph L Price | 9 | 28 | 3.45 |
Wayne C Drevets | 10 | 4 | 1.23 |