Title
Numerical optimization of a microfluidic assisted microarray for the detection of biochemical interactions.
Abstract
Finite element method analysis was applied to the characterization of the biomolecular interactions taking place in a microfluidic assisted microarray. Numerical simulations have been used for the optimization of geometrical and physical parameters of the sensing device. Different configurations have been analyzed and general considerations have been derived. We have shown that a parallel disposition of the sensing area allows the homogeneous formation of the target molecular complex in all the active zones of the microarray. Stationary and time dependent results have also been obtained.
Year
DOI
Venue
2011
10.3390/s111009658
SENSORS
Keywords
Field
DocType
microfluidics,biosensing,reaction kinetics
Analytical chemistry,Finite element method analysis,Homogeneous,Computer science,Microfluidics,Finite element method,Biosensor
Journal
Volume
Issue
ISSN
11
10
1424-8220
Citations 
PageRank 
References 
0
0.34
2
Authors
4
Name
Order
Citations
PageRank
Emanuele Orabona111.23
Ilaria Rea201.69
Ivo Rendina334.02
Luca De Stefano443.39