Title
In-Vivo Mri And In-Vivo Electro-Anatomical Voltage Map Characteristics Of Infarct Heterogeneity In A Swine Model
Abstract
The arrhythmogenic substrate in patients with prior myocardial infarct (MI) is located at the border zone, BZ. In this study we correlated the BZ identified by two methods: electro-anatomical voltage mapping (EAVM) and a novel MRI method, multi-contrast late enhancement (MCLE). A pre-clinical porcine model with chronic MI was used to characterize BZ via MRI and EAVM. Results focus on the comparison between scar percentage and BZ percentage identified by each method. The correlation coefficient for BZ percentage between the two methods was 0.74 with a p-value of less the 0.0001. Bland-Altman plots were also used to compare between the two methods (slope of 0.83 +/- 0.045). For a case of subtle infarct, there was only 1.3% infarct identified on EAVM compared to 22.2% on the corresponding slice on MCLE. The percentage of infarct on MCLE in subtle infarct does not relate to percentage of infarct in EAVM. Future registration between T-1 maps and EAVM will permit a quantitative comparison of MRI and EAVM measures.
Year
DOI
Venue
2011
10.1109/IEMBS.2011.6090764
2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Keywords
Field
DocType
magnetic resonance image,electrodes,myocardial infarct,image registration,magnetic resonance imaging,correlation
Nuclear medicine,Border zone,In vivo,Medicine,Magnetic resonance imaging
Conference
Volume
ISSN
Citations 
2011
1557-170X
1
PageRank 
References 
Authors
0.41
0
10
Name
Order
Citations
PageRank
E Shokrollahi110.75
M Pop210.41
M Safri310.41
Y Yang410.41
P E Radau510.41
Jennifer Barry692.76
Jay Detsky7142.33
G H Griffin810.41
Eugene Crystal9286.46
Graham A. Wright1012325.09