Title
Continuous computation in engineered gene circuits.
Abstract
In this paper we consider the problem of representation and measurement in genetic circuits, and investigate how they can affect the reliability of engineered systems. We propose a design scheme, based on the notion of continuous computation, which addresses these issues. We illustrate the methodology by showing how a concept from computer architecture (namely, branch prediction) may be implemented in vivo, using a distributed approach. Simulation results confirm the in-principle feasibility of our method, and offer valuable insights into its future laboratory validation.
Year
DOI
Venue
2012
10.1016/j.biosystems.2012.02.001
Biosystems
Keywords
Field
DocType
Synthetic biology,Computer architecture,Branch prediction
Computer science,Artificial intelligence,Electronic circuit,Gene regulatory network,Machine learning,Branch predictor,Synthetic biology,Engineered Gene,Computation
Journal
Volume
Issue
ISSN
109
1
0303-2647
Citations 
PageRank 
References 
3
0.61
4
Authors
2
Name
Order
Citations
PageRank
Ángel Goñi Moreno1195.70
Martyn Amos2131.71