Title
Population-based input function and image-derived input function for [C](R)-rolipram PET imaging: Methodology, validation and application to the study of major depressive disorder.
Abstract
Quantitative PET studies of neuroreceptor tracers typically require that arterial input function be measured. The aim of this study was to explore the use of a population-based input function (PBIF) and an image-derived input function (IDIF) for [11C](R)-rolipram kinetic analysis, with the goal of reducing – and possibly eliminating – the number of arterial blood samples needed to measure parent radioligand concentrations.
Year
DOI
Venue
2012
10.1016/j.neuroimage.2012.08.007
NeuroImage
Keywords
Field
DocType
Population-based input function,Image-derived input function,[11C](R)-rolipram,Major depressive disorder
Nuclear medicine,Developmental psychology,Population,Arterial blood,Psychology,Positron emission tomography,Major depressive disorder,Body surface area,Input function,Lean body mass,Analysis of variance
Journal
Volume
Issue
ISSN
63
3
1053-8119
Citations 
PageRank 
References 
4
0.71
7
Authors
11