Paper Info
Title
Cardiorespiratory Coupling During Sleep In Difficult-To-Control Asthmatic Patients
Abstract
Heart rate variability (HRV) and respiration recorded during sleep from 8 patients suffering from difficult-to-control asthma were studied to investigate autonomic nervous system control of cardiac and respiratory activities, and of cardio-respiratory coupling during different sleep stages.In healthy subjects, HRV monitoring during sleep reveals a predominant parasympathetic drive to the heart during non-rapid eye movement (NREM) sleep and an increased sympathetic activity during rapid eye movement (REM) sleep.Spectral analysis of HRV and cross-spectral analysis of HRV and respiration signals in the analyzed difficult-to-control asthma patients showed trends in the main spectral indices, which appeared similar to variations observed in non pathologic subjects, but which were possibly affected by a reduction in the sympathetic and cardiorespiratory modulations. The ratio between the tachogram power in the low frequency (LF) band and the tachogram power in the high frequency (HF) band, a marker of the sympatho-vagal balance, increased during deep sleep stage S3 (LF/HF = 0.855 +/- 0.876, mean +/- s.d.), indicating a predominance of the sympathetic component, and decreased during REM sleep (LF/HF = 0.748 +/- 0.716, mean +/- s.d.), indicating a drift of the sympatho-vagal balance towards the vagal component. The coherence between the tachogram and the respirogram in the HF band increased during deep sleep stages S2 (coherence = 0.855 +/- 0.727, mean +/- s.d.) and S4 (coherence = 0.843 +/- 0.724, mean +/- s.d.) and decreased during REM sleep (coherence = 0.808 +/- 0.719, mean +/- s.d.), suggesting that a stronger cardiorespiratory coupling was reached with synchronization of sleep.
Year
DOI
Venue
2012
10.1109/EMBC.2012.6346758
2012 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Keywords
Field
DocType
sleep,cardiology,neurophysiology
Autonomic nervous system,Asthma,Respiration,Sleep and breathing,Heart rate variability,Anesthesia,Respiratory system,Medicine,Sleep Stages,Cardiorespiratory fitness
Conference
Volume
ISSN
Citations 
2012
1557-170X
0
PageRank 
References 
Authors
0.34
0
10
Name
Order
Citations
PageRank
Ramona Cabiddu100.34
Aletti Federico221.44
Valeria Duarte Souza300.34
Ivan Peres Costa400.34
Roberto Stirbulov520.76
Audrey Borghi Silva620.76
Anna Maria Bianchi711915.44
Luis V Franco de Oliveira800.34
Sergio Cerutti900.34
Luciana Malosa Sampaio1020.76