Abstract | ||
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MicroRNAs (miRNAs) are small non-coding RNAs that regulate fundamental cellular processes in diverse organisms and that have an important function in gene expression regulation. miRNAs seem capable to concurrently modulate hundreds of target genes. Their abnormal expression is emerging as important element in many pathological conditions. The identification of microRNA binding sites on those proteins that can be disease biomarker is fundamental to design synthetic artificial oligomers. In this paper we suggest a method, based on signal processing, to filter out potential miRNA recognition sites in the 3' UTR region of mRNAs. |
Year | DOI | Venue |
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2012 | 10.1109/EMBC.2012.6347253 | 2012 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) |
Keywords | Field | DocType |
signal processing,proteins,genetics,pattern recognition,molecular biophysics,rna | RNA,Untranslated region,Gene,Biology,Biomarker (medicine),Artificial intelligence,Computational biology,Three prime untranslated region,Computer vision,microRNA,Regulation of gene expression,Molecular biophysics,Bioinformatics | Conference |
Volume | ISSN | Citations |
2012 | 1557-170X | 0 |
PageRank | References | Authors |
0.34 | 3 | 3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Norbert Maggi | 1 | 0 | 1.69 |
Patrizio Arrigo | 2 | 0 | 0.34 |
Carmelina Ruggiero | 3 | 13 | 5.48 |