Title
Stroke damage detection using classification trees on electrical bioimpedance cerebral spectroscopy measurements.
Abstract
After cancer and cardio-vascular disease, stroke is the third greatest cause of death worldwide. Given the limitations of the current imaging technologies used for stroke diagnosis, the need for portable non-invasive and less expensive diagnostic tools is crucial. Previous studies have suggested that electrical bioimpedance (EBI) measurements from the head might contain useful clinical information related to changes produced in the cerebral tissue after the onset of stroke. In this study, we recorded 720 EBI Spectroscopy (EBIS) measurements from two different head regions of 18 hemispheres of nine subjects. Three of these subjects had suffered a unilateral haemorrhagic stroke. A number of features based on structural and intrinsic frequency-dependent properties of the cerebral tissue were extracted. These features were then fed into a classification tree. The results show that a full classification of damaged and undamaged cerebral tissue was achieved after three hierarchical classification steps. Lastly, the performance of the classification tree was assessed using Leave-One-Out Cross Validation (LOO-CV). Despite the fact that the results of this study are limited to a small database, and the observations obtained must be verified further with a larger cohort of patients, these findings confirm that EBI measurements contain useful information for assessing on the health of brain tissue after stroke and supports the hypothesis that classification features based on Cole parameters, spectral information and the geometry of EBIS measurements are useful to differentiate between healthy and stroke damaged brain tissue.
Year
DOI
Venue
2013
10.3390/s130810074
SENSORS
Keywords
Field
DocType
stroke,electrical bioimpedance spectroscopy,classification tree,cole parameters
Biomedical engineering,Stroke,Electronic engineering,Haemorrhagic stroke,Radiology,Engineering,Cross-validation,Brain tissue,Diagnostic tools
Journal
Volume
Issue
ISSN
13
8.0
1424-8220
Citations 
PageRank 
References 
3
0.66
5
Authors
4
Name
Order
Citations
PageRank
S R Atefi161.49
Fernando Seoane2507.47
Thorleif Thorlin330.66
Kaj Lindecrantz4369.52