Title
Tracking Progression Of Patient State Of Health In Critical Care Using Inferred Shared Dynamics In Physiological Time Series
Abstract
Physiologic systems generate complex dynamics in their output signals that reflect the changing state of the underlying control systems. In this work, we used a switching vector autoregressive (switching VAR) framework to systematically learn and identify a collection of vital sign dynamics, which can possibly be recurrent within the same patient and shared across the entire cohort. We show that these dynamical behaviors can be used to characterize and elucidate the progression of patients' states of health over time. Using the mean arterial blood pressure time series of 337 ICU patients during the first 24 hours of their ICU stays, we demonstrated that the learned dynamics from as early as the first 8 hours of patients' ICU stays can achieve similar hospital mortality prediction performance as the well-known SAPS-I acuity scores, suggesting that the discovered latent dynamics structure may yield more timely insights into the progression of a patient's state of health than the traditional snapshot-based acuity scores.
Year
DOI
Venue
2013
10.1109/EMBC.2013.6611187
2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Keywords
DocType
Volume
time series analysis,blood pressure,health care,hidden markov models,switches,blood pressure measurement,time series
Conference
2013
ISSN
Citations 
PageRank 
1557-170X
2
0.56
References 
Authors
1
6
Name
Order
Citations
PageRank
Li-wei H Lehman119218.54
Shamim Nemati27117.97
Ryan P. Adams32286131.88
George Moody420.56
Atul Malhotra520.56
rodger g mark620.56