Title
Cortical Correspondence via Sulcal Curve-Constrained Spherical Registration with Application to Macaque Studies.
Abstract
In this work, we present a novel cortical correspondence method with application to the macaque brain. The correspondence method is based on sulcal curve constraints on a spherical deformable registration using spherical harmonics to parameterize the spherical deformation. Starting from structural MR images, we first apply existing preprocessing steps: brain tissue segmentation using the Automatic Brain Classification tool (ABC), as well as cortical surface reconstruction and spherical parametrization of the cortical surface via Constrained Laplacian-based Automated Segmentation with Proximities (CLASP). Then, initial correspondence between two cortical surfaces is automatically determined by a curve labeling method using sulcal landmarks extracted along sulcal fundic regions. Since the initial correspondence is limited to sulcal regions, we use spherical harmonics to extrapolate and regularize this correspondence to the entire cortical surface. To further improve the correspondence, we compute a spherical registration that optimizes the spherical harmonic parameterized deformation using a metric that incorporates the error over the sulcal landmarks as well as the normalized cross correlation of sulcal depth maps over the whole cortical surface. For evaluation, a normal 18-months-old macaque brain (for both left and right hemispheres) was matched to a prior macaque brain template with 9 manually labeled, major sulcal curves. The results show successful registration using the proposed registration approach. Evaluation results for optimal parameter settings are presented as well.
Year
DOI
Venue
2013
10.1117/12.2006459
Proceedings of SPIE
Keywords
Field
DocType
cortical correspondence,surface registration,spherical harmonics,sulcal curve
Cross-correlation,Computer vision,Surface reconstruction,Macaque,Parametrization,Segmentation,Spherical harmonics,Preprocessor,Artificial intelligence,Physics,Laplace operator
Conference
Volume
ISSN
Citations 
8669
0277-786X
2
PageRank 
References 
Authors
0.39
0
9
Name
Order
Citations
PageRank
Ilwoo Lyu130.74
Sun Hyung Kim220.39
Joon-Kyung Seong320.39
Sang Wook Yoo460.96
Alan Evans579942.82
Yundi Shi620.39
Mar Sanchez770.86
Marc Niethammer873168.16
Styner Martin9184.33