Title
White blood cell segmentation by color-space-based k-means clustering.
Abstract
White blood cell (WBC) segmentation, which is important for cytometry, is a challenging issue because of the morphological diversity of WBCs and the complex and uncertain background of blood smear images. This paper proposes a novel method for the nucleus and cytoplasm segmentation of WBCs for cytometry. A color adjustment step was also introduced before segmentation. Color space decomposition and k-means clustering were combined for segmentation. A database including 300 microscopic blood smear images were used to evaluate the performance of our method. The proposed segmentation method achieves 95.7% and 91.3% overall accuracy for nucleus segmentation and cytoplasm segmentation, respectively. Experimental results demonstrate that the proposed method can segment WBCs effectively with high accuracy.
Year
DOI
Venue
2014
10.3390/s140916128
SENSORS
Keywords
Field
DocType
white blood cell,segmentation,color space decomposition,k-means clusters
k-means clustering,Computer vision,Color space,Biology,Segmentation,Artificial intelligence,Image Cytometry,Cluster analysis,White blood cell,Cytometry
Journal
Volume
Issue
ISSN
14
9.0
1424-8220
Citations 
PageRank 
References 
8
0.72
6
Authors
8
Name
Order
Citations
PageRank
Congcong Zhang180.72
Xiaoyan Xiao2161.64
Xiaomei Li3161.65
Ying-Jie Chen480.72
Wu Zhen580.72
Jun Chang6151.29
Chengyun Zheng7151.29
Zhi Liu82314.28