Title
Computerized methodology for micro-CT and histological data inflation using an IVUS based translation map.
Abstract
A framework for the inflation of micro-CT and histology data using intravascular ultrasound (IVUS) images, is presented. The proposed methodology consists of three steps. In the first step the micro-CT/histological images are manually co-registered with IVUS by experts using fiducial points as landmarks. In the second step the lumen of both the micro-CT/histological images and IVUS images are automatically segmented. Finally, in the third step the micro-CT/histological images are inflated by applying a transformation method on each image. The transformation method is based on the IVUS and micro-CT/histological contour difference. In order to validate the proposed image inflation methodology, plaque areas in the inflated micro-CT and histological images are compared with the ones in the IVUS images. The proposed methodology for inflating micro-CT/histological images increases the sensitivity of plaque area matching between the inflated and the IVUS images (7% and 22% in histological and micro-CT images, respectively).
Year
DOI
Venue
2015
10.1016/j.compbiomed.2015.02.018
Computers in Biology and Medicine
Keywords
DocType
Volume
Micro-CT,Histology,Intravascular ultrasound,Plaque characterization,Image registration
Journal
65
Issue
ISSN
Citations 
C
0010-4825
0
PageRank 
References 
Authors
0.34
6
12