Title
Tfmir: A Web Server For Constructing And Analyzing Disease-Specific Transcription Factor And Mirna Co-Regulatory Networks
Abstract
TFmiR is a freely available web server for deep and integrative analysis of combinatorial regulatory interactions between transcription factors, microRNAs and target genes that are involved in disease pathogenesis. Since the inner workings of cells rely on the correct functioning of an enormously complex system of activating and repressing interactions that can be perturbed in many ways, TFmiR helps to better elucidate cellular mechanisms at the molecular level from a network perspective. The provided topological and functional analyses promote TFmiR as a reliable systems biology tool for researchers across the life science communities. TFmiR web server is accessible through the following URL: http://service.bioinformatik.uni-saarland.de/tfmir.
Year
DOI
Venue
2015
10.1093/nar/gkv418
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Disease,Biology,Systems biology,Candidate Disease Gene,Bioinformatics,Computational biology,Genetics,Gene regulatory network,Transcription factor,Web server,The Internet
Journal
43
Issue
ISSN
Citations 
W1
0305-1048
5
PageRank 
References 
Authors
0.50
22
4
Name
Order
Citations
PageRank
Mohamed Hamed171.62
Christian Spaniol251.18
Maryam Nazarieh371.95
Volkhard Helms452.87