Title
Microfluidic very large-scale integration for biochips: Technology, testing and fault-tolerant design
Abstract
Microfluidic biochips are replacing the conventional biochemical analyzers by integrating all the necessary functions for biochemical analysis using microfluidics. Biochips are used in many application areas, such as, in vitro diagnostics, drug discovery, biotech and ecology. The focus of this paper is on continuous-flow biochips, where the basic building block is a microvalve. By combining these microvalves, more complex units such as mixers, switches, multiplexers can be built, hence the name of the technology, “microfluidic Very Large-Scale Integration” (mVLSI). A roadblock in the deployment of microfluidic biochips is their low reliability and lack of test techniques to screen defective devices before they are used for biochemical analysis. Defective chips lead to repetition of experiments, which is undesirable due to high reagent cost and limited availability of samples. This paper presents the state-of-the-art in the mVLSI platforms and emerging research challenges in the area of continuous-flow microfluidics, focusing on testing techniques and fault-tolerant design.
Year
DOI
Venue
2015
10.1109/ETS.2015.7138736
European Test Symposium
Keywords
Field
DocType
VLSI,bioMEMS,biochemistry,biomedical equipment,lab-on-a-chip,microfluidics,microvalves,multiplexing equipment,biochemical analysis,biochemical analyzers,biotech,continuous-flow microfluidics,drug discovery,ecology,fault-tolerant design,in vitro diagnostics,mVLSI platforms,microfluidic biochips,microfluidic very large-scale integration,microvalve,mixers,multiplexers,screen defective devices,switches
Biochip,Computer science,Microfluidics,Electronic engineering,Multiplexer,Fault tolerance,Very-large-scale integration
Conference
Citations 
PageRank 
References 
3
0.48
11
Authors
3
Name
Order
Citations
PageRank
Ismail Emre Araci130.82
Paul Pop289968.16
K Chakrabarty38173636.14