Title
A compressive sensing spectral model for fNIRS haemodynamic response de-noising
Abstract
In the biomedical scenario, near-infrared spectroscopy (NIRS) is employed as a non-invasive brain imaging technique. In particular, functional near-infrared spectroscopy (fNIRS) measures the brain response, also known as haemodynamic response (HR), to pre-defined stimuli. Processing of fNIRS data requires a great effort to extrapolate the informative component from a noisy mixture of physiological and spurious contributions. In this paper a novel fNIRS de-noising algorithm is presented and validated over both synthetic ideal and synthetic realistic data. The short-separation channel signal is divided into nonoverlapping short sequences. For each of them, a specific noise model is identified and subtracted from the corresponding standard channel data. The algorithm relies on a combination of a super-resolution technique based on Compressive Sensing theory and spectral analysis performed via Taylor-Fourier transform. Preliminary experimental results show a significant reduction of spurious components in all the considered conditions. No significant distortions are introduced in the recovered HR, ensuring reliable clinical interpretation of the acquired trace.
Year
DOI
Venue
2015
10.1109/MeMeA.2015.7145207
Medical Measurements and Applications
Keywords
Field
DocType
Fourier transforms,brain,compressed sensing,haemodynamics,infrared spectroscopy,medical signal processing,signal denoising,spectral analysis,Compressive Sensing theory,HR,Taylor-Fourier transform,brain response,compressive sensing spectral model,fNIRS denoising algorithm,fNIRS haemodynamic response denoising,functional near-infrared spectroscopy,informative component,noisy mixture,noninvasive brain imaging technique,nonoverlapping short sequences,physiological contribution,predefined stimuli,short-separation channel signal,specific noise model,spectral analysis,spurious contribution,standard channel data,super-resolution technique,synthetic ideal data,synthetic realistic data,Taylor-Fourier transform,compressive sensing,de-noising,functional near-infrared spectroscopy,super-resolution
Biomedical engineering,Haemodynamic response,Speech recognition,Neuroimaging,Spectroscopy,Spurious relationship,Materials science,Compressed sensing
Conference
Citations 
PageRank 
References 
2
0.38
9
Authors
4
Name
Order
Citations
PageRank
guglielmo frigo15510.64
Brigadoi, S.220.38
Giorgi, G.320.38
Sparacino, G.420.38