Paper Info
Title
Transcranial electrical stimulation of the occipital cortex during visual perception modifies the magnitude of BOLD activity: A combined tES-fMRI approach.
Abstract
The aim of this study was to investigate if the blood oxygenation level-dependent (BOLD) changes in the visual cortex can be used as biomarkers reflecting the online and offline effects of transcranial electrical stimulation (tES). Anodal transcranial direct current stimulation (tDCS) and 10Hz transcranial alternating current stimulation (tACS) were applied for 10min duration over the occipital cortex of healthy adults during the presentation of different visual stimuli, using a crossover, double-blinded design. Control experiments were also performed, in which sham stimulation as well as another electrode montage were used. Anodal tDCS over the visual cortex induced a small but significant further increase in BOLD response evoked by a visual stimulus; however, no aftereffect was observed. Ten hertz of tACS did not result in an online effect, but in a widespread offline BOLD decrease over the occipital, temporal, and frontal areas. These findings demonstrate that tES during visual perception affects the neuronal metabolism, which can be detected with functional magnetic resonance imaging (fMRI).
Year
DOI
Venue
2016
10.1016/j.neuroimage.2015.11.034
NeuroImage
Keywords
Field
DocType
tDCS,tACS,fMRI,Occipital cortex,Visual perception
Cortex (botany),Neuroscience,Visual cortex,Functional magnetic resonance imaging,Transcranial alternating current stimulation,Psychology,Cognitive psychology,Stimulus (physiology),Transcranial direct-current stimulation,Stimulation,Visual perception
Journal
Volume
ISSN
Citations 
140
1053-8119
1
PageRank 
References 
Authors
0.48
6
4
Name
Order
Citations
PageRank
Ivan Alekseichuk111.16
Kersten Diers210.48
Walter Paulus3546.45
Andrea Antal4384.64