Name
Title | ||
|---|---|---|
Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic calibration. |
Abstract | ||
|---|---|---|
Several techniques have been proposed to estimate relative changes in cerebral metabolic rate of oxygen consumption (CMRO2) by exploiting combined BOLD fMRI and cerebral blood flow data in conjunction with hypercapnic or hyperoxic respiratory challenges. More recently, methods based on respiratory challenges that include both hypercapnia and hyperoxia have been developed to assess absolute CMRO2, an important parameter for understanding brain energetics. In this paper, we empirically optimize a previously presented “original calibration model” relating BOLD and blood flow signals specifically for the estimation of oxygen extraction fraction (OEF) and absolute CMRO2. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1016/j.neuroimage.2016.01.021 | NeuroImage |
Keywords | Field | DocType |
Calibrated BOLD,Mathematical modelling,Cerebral metabolic rate of oxygen consumption,Functional MRI,Respiratory tasks | Cerebral blood volume,Propagation of uncertainty,Blood flow,Biological system,Simulation,Psychology,Cognitive psychology,Oxygen extraction,Cerebral blood flow,Calibration,Observational error,Design of experiments | Journal |
Volume | ISSN | Citations |
129 | 1053-8119 | 9 |
PageRank | References | Authors |
0.51 | 9 | 8 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Alberto Merola | 1 | 14 | 1.60 |
| Kevin Murphy | 2 | 316 | 32.69 |
| Alan J. Stone | 3 | 46 | 3.41 |
| Michael A. Germuska | 4 | 74 | 4.99 |
| Valerie E M Griffeth | 5 | 9 | 0.51 |
| Nicholas Blockley | 6 | 99 | 8.41 |
| Richard B Buxton | 7 | 19 | 1.74 |
| Richard G. Wise | 8 | 319 | 38.18 |