Title
An automatic system to identify heart disease risk factors in clinical texts over time
Abstract
Despite recent progress in prediction and prevention, heart disease remains a leading cause of death. One preliminary step in heart disease prediction and prevention is risk factor identification. Many studies have been proposed to identify risk factors associated with heart disease; however, none have attempted to identify all risk factors. In 2014, the National Center of Informatics for Integrating Biology and Beside (i2b2) issued a clinical natural language processing (NLP) challenge that involved a track (track 2) for identifying heart disease risk factors in clinical texts over time. This track aimed to identify medically relevant information related to heart disease risk and track the progression over sets of longitudinal patient medical records. Identification of tags and attributes associated with disease presence and progression, risk factors, and medications in patient medical history were required. Our participation led to development of a hybrid pipeline system based on both machine learning-based and rule-based approaches. Evaluation using the challenge corpus revealed that our system achieved an F1-score of 92.68%, making it the top-ranked system (without additional annotations) of the 2014 i2b2 clinical NLP challenge. © 2015 Elsevier Inc.
Year
DOI
Venue
2015
10.1016/j.jbi.2015.09.002
Journal of Biomedical Informatics
Keywords
Field
DocType
Clinical information extraction,Heart disease,Machine learning,Risk factor identification
Data mining,Informatics,Disease,Risk assessment,Risk management,Medical history,Medicine,Cohort study,Risk factor,Heart disease
Journal
Volume
Issue
ISSN
58
SUPnan
1532-0464
Citations 
PageRank 
References 
6
0.44
21
Authors
12
Name
Order
Citations
PageRank
Qingcai Chen180966.72
Li Haodi2253.89
Buzhou Tang336834.04
Xiaolong Wang41208115.39
Xin Liu53919320.56
Zengjian Liu6353.84
Shu Liu713418.46
Wang Weida861.45
qiwen9202.10
Zhu Suisong10161.34
Chen Yangxin11161.01
Wang Jingfeng12161.01