Title
KnowEnG: a knowledge engine for genomics.
Abstract
We describe here the vision, motivations, and research plans of the National Institutes of Health Center for Excellence in Big Data Computing at the University of Illinois, Urbana-Champaign. The Center is organized around the construction of "Knowledge Engine for Genomics" (KnowEnG), an E-science framework for genomics where biomedical scientists will have access to powerful methods of data mining, network mining, and machine learning to extract knowledge out of genomics data. The scientist will come to KnowEnG with their own data sets in the form of spreadsheets and ask KnowEnG to analyze those data sets in the light of a massive knowledge base of community data sets called the "Knowledge Network" that will be at the heart of the system. The Center is undertaking discovery projects aimed at testing the utility of KnowEnG for transforming big data to knowledge. These projects span a broad range of biological enquiry, from pharmacogenomics (in collaboration with Mayo Clinic) to transcriptomics of human behavior.
Year
DOI
Venue
2015
10.1093/jamia/ocv090
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
Keywords
Field
DocType
BD2K,Network analysis,genomics,big data,scalable
Data science,Data mining,Network mining,Knowledge management,Genomics,Datasets as Topic,Knowledge base,Medicine,Excellence,Big data,Scalability
Journal
Volume
Issue
ISSN
22
6
1067-5027
Citations 
PageRank 
References 
2
0.39
15
Authors
5
Name
Order
Citations
PageRank
Saurabh Sinha152948.96
Jun S. Song2163.46
Richard M. Weinshilboum3153.10
C Victor Jongeneel413721.43
Jiawei Han5430853824.48