Paper Info
Title
A patient-specific visualization tool for comprehensive analysis of coronary CTA and perfusion MRI data
Abstract
Cardiac magnetic resonance perfusion imaging (CMR) and computed tomography angiography (CTA) are widely used to assess heart disease. CMR is used to measure the global and regional myocardial function and to evaluate the presence of ischemia; CTA is used for diagnosing coronary artery disease, such as coronary stenoses. Nowadays, the hemodynamic significance of coronary artery stenoses is determined subjectively by combining information on myocardial function with assumptions on coronary artery territories. As the anatomy of coronary arteries varies greatly between individuals, we developed a patient-specific tool for relating CTA and perfusion CMR data. The anatomical and functional information extracted from CTA and CMR data are combined into a single frame of reference. Our graphical user interface provides various options for visualization. In addition to the standard perfusion Bull's Eye Plot (BEP), it is possible to overlay a 2D projection of the coronary tree on the BEP, to add a 3D coronary tree model and to add a 3D heart model. The perfusion BEP, the 3D-models and the CTA data are also interactively linked. Using the CMR and CTA data of 14 patients, our tool directly established a spatial correspondence between diseased coronary artery segments and myocardial regions with abnormal perfusion. The location of coronary stenoses and perfusion abnormalities were visualized jointly in 3D, thereby facilitating the study of the relationship between the anatomic causes of a blocked artery and the physiological effects on the myocardial perfusion. This tool is expected to improve diagnosis and therapy planning of early-stage coronary artery disease.
Year
DOI
Venue
2011
10.1117/12.873050
Proceedings of SPIE
Keywords
Field
DocType
Computed Tomography Angiography (CTA),Cardiac Magnetic Resonance perfusion imaging (CMR),Coronary Artery Disease (CAD),diagnosis,visualization
Coronary artery disease,Computed tomography angiography,Visualization,Cardiac magnetic resonance,Radiology,Medicine,Perfusion
Conference
Volume
ISSN
Citations 
7964
0277-786X
1
PageRank 
References 
Authors
0.40
4
10
Name
Order
Citations
PageRank
Hortense Kirisli1142.11
V. K. Gupta29112.72
Sharon W. Kirschbaum331.11
Lisan Neefjes4695.94
Robert Jan van Geuns5553.99
Nico R Mollet61175.74
B.P.F. Lelieveldt71331115.59
Johan H. C. Reiber81767286.53
Theo van Walsum991285.34
Wiro J. Niessen103821380.78