Title
Investigation of temporal radiographic texture analysis for the detection of periprosthetic osteolysis
Abstract
Periprosthetic osteolysis is a disease caused by the body's response to submicron polyethylene debris particles from the hip implant in total hip replacement (THR) patients. It leads to resorption of bone surrounding the implant and deterioration of the bone's trabecular texture, but this is difficult to detect until the later stages of disease progression. Radiographic texture analysis methods have shown promise in detecting this disease at an earlier stage; however, changes in texture over time may be more important than absolute texture measures. In this research, we investigated temporal radiographic texture analysis (tRTA) methods as possible aids in the detection of osteolysis. A database of 48 THR cases with images available from four different follow-up time intervals was used. ROls were selected within the osteolytic region of the most recent follow-up image (or comparable region for normal cases) and visually matched on all previous images. Texture features were calculated from the ROls and then trend analysis was performed using a simple linear regression method, an LDA method and a BANN method. The performance of these three methods was evaluated by ROC analysis. Maximum AUC values of 0.68, 0.78, and 0.88 for the task of distinguishing between osteolysis and normal cases were achieved for the respective tRTA features. These performances were superior to those of our prior stationary, non-temporal texture analysis. The results suggest that tRTA may have the potential to help detect osteolysis at an earlier, more treatable stage.
Year
DOI
Venue
2006
10.1117/12.653594
Proceedings of SPIE
Keywords
Field
DocType
computer-aided diagnosis,texture,temporal trends,orthopedics
Biomedical engineering,Osteolysis,Implant,Computer-aided diagnosis,Disease progression,Radiography,Radiology,Orthopedic surgery,Periprosthetic osteolysis,Hip implant,Materials science
Conference
Volume
ISSN
Citations 
6144
0277-786X
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
joel r wilkie111.11
Maryellen L. Giger239385.89
charles a engh300.68
john m martell400.68