Title
Dual-projection 3D-2D registration for surgical guidance: preclinical evaluation of performance and minimum angular separation
Abstract
An algorithm for 3D-2D registration of CT and x-ray projections has been developed using dual projection views to provide 3D localization with accuracy exceeding that of conventional tracking systems. The registration framework employs a normalized gradient information (NGI) similarity metric and covariance matrix adaptation evolution strategy (CMA-ES) to solve for the patient pose in 6 degrees of freedom. Registration performance was evaluated in anthropomorphic head and chest phantoms, as well as a human torso cadaver, using C-arm projection views acquired at angular separations (Delta theta) ranging 0-178 degrees. Registration accuracy was assessed in terms target registration error (TRE) and compared to that of an electromagnetic tracker. Studies evaluated the influence of C-arm magnification, x-ray dose, and preoperative CT slice thickness on registration accuracy and the minimum angular separation required to achieve TRE similar to 2 mm. The results indicate that Delta theta as small as 10-20 degrees is adequate to achieve TRE <2 mm with 95% confidence, comparable or superior to that of commercial trackers. The method allows direct registration of preoperative CT and planning data to intraoperative fluoroscopy, providing 3D localization free from conventional limitations associated with external fiducial markers, stereotactic frames, trackers, and manual registration. The studies support potential application to percutaneous spine procedures and intracranial neurosurgery.
Year
DOI
Venue
2014
10.1117/12.2043561
Proceedings of SPIE
Keywords
Field
DocType
Image-guided surgery,3D-2D image registration,C-arm imaging,neurosurgery,orthopaedic surgery
Computer vision,Torso,Fiducial marker,Image-guided surgery,Tracking system,Fluoroscopy,Artificial intelligence,CMA-ES,Magnification,Image registration,Physics
Conference
Volume
ISSN
Citations 
9036
0277-786X
0
PageRank 
References 
Authors
0.34
4
11
Name
Order
Citations
PageRank
Ali Uneri111323.38
Yoshito Otake214428.20
Adam S. Wang373.27
G Kleinszig43512.24
sebastian vogt534.20
G L Gallia6718.13
Daniele Rigamonti721.06
j p wolinsky842.83
ziya l gokaslan910.77
a j khanna1052.98
J H Siewerdsen1110028.22