Title
Evaluation of the use of multimodality skin markers for the registration of pre-procedure cardiac MR images and intra-procedure x-ray fluoroscopy images for image guided cardiac electrophysiology procedures
Abstract
This paper presents the evaluation of the use of multimodality skin markers for the registration of cardiac magnetic resonance (MR) image data to x-ray fluoroscopy data for the guidance of cardiac electrophysiology procedures. The approach was validated using a phantom study and 3 patients undergoing pulmonary vein (PV) isolation for the treatment of paroxysmal atrial fibrillation. In the patient study, skin markers were affixed to the patients' chest and used to register pre-procedure cardiac MR image data to intra-procedure fluoroscopy data. Registration errors were assessed using contrast angiograms of the left atrium that were available in 2 out of 3 cases. A clinical expert generated "gold standard" registrations by adjusting the registration manually. Target registration errors (TREs) were computed using points on the PV ostia. Ablation locations were computed using biplane x-ray imaging. Registration errors were further assessed by computing the distances of the ablation points to the registered left atrial surface for all 3 patients. The TREs were 6.0 & 3.1 mm for patients 1 & 2. The mean ablation point errors were 6.2, 3.8, & 3.0mm for patients 1, 2, & 3. These results are encouraging in the context of a 5mm clinical accuracy requirement for this type of procedure. We conclude that multimodality skin markers have the potential to provide anatomical image integration for x-ray guided cardiac electrophysiology procedures, especially if coupled with an accurate respiratory motion compensation strategy.
Year
DOI
Venue
2008
10.1117/12.770172
PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE)
Keywords
DocType
Volume
cardiac procedures,image-guided therapy,multimodality display,registration,validation
Conference
6918
ISSN
Citations 
PageRank 
0277-786X
6
0.88
References 
Authors
2
11
Name
Order
Citations
PageRank
Kawal Rhode115021.01
YingLiang Ma225126.76
angela chandrasena360.88
Andrew P. King448359.98
Gang Gao59210.45
Phani Chinchapatnam618618.55
Maxime Sermesant71111122.97
David J. Hawkes84262470.26
Tobias Schaeffter947251.54
Jaswinder Gill10858.47
Reza Razavi1192994.25