Title
Segmentation of the thalamus in multi-spectral MR images using a combination of atlas-based and gradient graph cut methods
Abstract
Two popular segmentation methods used today are atlas based and graph cut based segmentation techniques. The atlas based method deforms a manually segmented image onto a target image, resulting in an automatic segmentation. The graph cut segmentation method utilizes the graph cut paradigm by treating image segmentation as a max-flow problem. A specialized form of this algorithm was developed by Lecoeur et al [1], called the spectral graph cut algorithm. The goal of this paper is to combine both of these methods, creating a more stable atlas based segmentation algorithm that is less sensitive to the initial manual segmentation. The registration algorithm is used to automate and initialize the spectral graph cut algorithm as well as add needed spatial information, while the spectral graph cut algorithm is used to increase the robustness of the atlas method. To calculate the sensitivity of the algorithms, the initial manual segmentation of the atlas was both dilated and eroded 2 mm and the segmentation results were calculated. Results show that the atlas based segmentation segments the thalamus well with an average Dice Similarity Coefficient (DSC) of 0.87. The spectral graph cut method shows similar results with an average DSC measure of 0.88, with no statistical difference between the two methods. The atlas based method's DSC value, however, was reduced to 0.76 and 0.67 when dilated and eroded respectively, while the combined method retained a DSC value of 0.81 and 0.74, with a statistical difference found between the two methods.
Year
DOI
Venue
2010
10.1117/12.844183
Proceedings of SPIE
Keywords
Field
DocType
ABA,non-rigid registration,thalamus segmentation,graph cut,spectral gradient
Cut,Computer vision,Scale-space segmentation,Pattern recognition,Segmentation,Segmentation-based object categorization,Image segmentation,Robustness (computer science),Atlas (anatomy),Artificial intelligence,Minimum spanning tree-based segmentation,Physics
Conference
Volume
ISSN
Citations 
7623
0277-786X
1
PageRank 
References 
Authors
0.36
17
4
Name
Order
Citations
PageRank
Ryan D. Datteri1283.87
christian barillot226489.64
Benoit M. Dawant31388223.11
Jeremy Lecoeur4222.63