Paper Info
Title
Image analysis of pulmonary nodules using micro CT
Abstract
We are developing a micro-computed tomography (micro CT) system for imaging pulmonary nodules. The purpose is to enhanced the physician performance in accessing the micro architecture of the nodule for classification between malignant and benign nodules. The basic components of the micro CT system consist of a microfocus X-ray source, a specimen manipulator, and an image intensifier detector coupled to charge-coupled device (CCD) camera. Three-dimensional (3-D) image reconstruction was performed slice by slice. A standard fan-beam convolution and backprojection algorithm was used to reconstruct the center plane intersecting the X-ray source. The preprocessing of the 3-D image reconstruction included the correction of the geometrical distortions and the shading artifact introduced by the image intensifier. The main advantage of the system is to obtain a high spatial resolution which ranges between 5 mu m and 25 mu m. In this work we report on preliminary studies performed with the micro CT for imaging resected tissues of normal and abnormal lung. Experimental results reveal micro architecture of lung tissues, such as alveolar wall, septal wall of pulmonary lobule, and bronchiole. From the results, the micro CT system is expected to have interesting potentials for high confidential differential diagnosis.
Year
DOI
Venue
2001
10.1117/12.431149
Proceedings of SPIE
Keywords
Field
DocType
micro CT,pulmonary nodule,lung tissue,differential diagnosis,micro architecture
Computer vision,Computer science,Convolution,Shading Artifact,Tomography,Pulmonary Lobule,Artificial intelligence,Image resolution,Detector,Image intensifier,3d image reconstruction
Conference
Volume
ISSN
Citations 
4322
0277-786X
0
PageRank 
References 
Authors
0.34
0
7
Name
Order
Citations
PageRank
Noboru Niki118866.10
Yoshiki Kawata219254.44
masashi fujii300.68
Ryutaro Kakinuma49724.90
Noriyuki Moriyama514850.47
Yukio Tateno67914.41
eisuke matsui700.68