Title
Evaluation of COPD's diaphragm motion extracted from 4D-MRI
Abstract
We have developed a method called intersection profile method to construct a 4D-MRI (3D+time) from time-series of 2D-MRI. The basic idea is to find the best matching of the intersection profile from the time series of 2D-MRI in sagittal plane (navigator slice) and time series of 2D-MRI in coronal plane (data slice). In this study, we use 4D-MRI to semiautomatically extract the right diaphragm motion of 16 subjects (8 healthy subjects and 8 COPD patients). The diaphragm motion is then evaluated quantitatively by calculating the displacement of each subjects and normalized it. We also generate phase-length map to view and locate paradoxical motion of the COPD patients. The quantitative results of the normalized displacement shows that COPD patients tend to have smaller displacement compared to healthy subjects. The average normalized displacement of total 8 COPD patients is 9.4mm and the average of normalized displacement of 8 healthy volunteers is 15.3mm. The generated phase-length maps show that not all of the COPD patients have paradoxical motion, however if it has paradoxical motion, the phase-length map is able to locate where does it occur.
Year
DOI
Venue
2015
10.1117/12.2081090
Proceedings of SPIE
Keywords
Field
DocType
4D-MRI,diaphragm motion,COPD
Biomedical engineering,COPD,Computer vision,Diaphragm (structural system),Coronal plane,Simulation,Data slice,Artificial intelligence,Sagittal plane,Magnetic resonance imaging,Physics
Conference
Volume
ISSN
Citations 
9413
0277-786X
0
PageRank 
References 
Authors
0.34
2
12