Title
Correlative feature analysis of FFDM images
Abstract
Identifying the corresponding image pair of a lesion is an essential step for combining information from different views of the lesion to improve the diagnostic ability of both radiologists and CAD systems. Because of the non-rigidity of the breasts and the 2D projective property of mammograms, this task is not trivial. In this study, we present a computerized framework that differentiates the corresponding images from different views of a lesionfrom non-corresponding ones. A dual-stage segmentation method, which employs an initial radial gradient index (RGI) based segmentation and an active contour model, was initially applied to extract mass lesions from the surrounding tissues. Then various lesion features were automatically extracted from each of the two views of each lesion to quantify the characteristics of margin, shape, size, texture and context of the lesion, as well as its distance to nipple. We employed a two-step method to select an effective subset of features, and combined it with a BANN to obtain a discriminant score, which yielded an estimate of the probability that the two images are of the same physical lesion. ROC analysis was used to evaluate the performance of the individual features and the selected feature subset in the task of distinguishing between corresponding and non-corresponding pairs. By using a FFDM database with 124 corresponding image pairs and 35 non-corresponding pairs, the distance feature yielded an AUC (area under the ROC curve) of 0.8 with leave-one-out evaluation by lesion, and the feature subset, which includes distance feature, lesion size and lesion contrast, yielded an AUC of 0.86. The improvement by using multiple features was statistically significant as compared to single feature performance. (p < 0.001).
Year
DOI
Venue
2008
10.1117/12.770524
PROCEEDINGS OF THE SOCIETY OF PHOTO-OPTICAL INSTRUMENTATION ENGINEERS (SPIE)
Keywords
Field
DocType
mammography,correlative feature analysis,computer-aided diagnosis
Correlative,Active contour model,Computer vision,Mammography,Lesion,Pattern recognition,Computer science,Discriminant,Segmentation,Computer-aided diagnosis,Artificial intelligence,Pattern recognition (psychology)
Conference
Volume
ISSN
Citations 
6915
0277-786X
2
PageRank 
References 
Authors
0.39
0
4
Name
Order
Citations
PageRank
Yading Yuan1696.62
Maryellen L. Giger239385.89
Hui Li34515.48
Charlene A. Sennett4133.08