Paper Info
Title
Low-dose dual-energy electronic cleansing for fecal-tagging CT Colonography
Abstract
Dual-energy electronic cleansing (DE-EC) provides a promising means for cleansing the tagged fecal materials in fecal-tagging CT colonography (CTC). However, the increased radiation dose due to the double exposures in dual-energy CTC (DE-CTC) scanning is a major limitation for the use of DE-EC in clinical practice. The purpose of this study was to develop and evaluate a low-dose DE-EC scheme in fecal-tagging DE-CTC. In this study, a custom-made anthropomorphic colon phantom, which was filled with simulated tagged materials by non-ionic iodinated contrast agent (Omnipaque iohexol, GE Healthcare), was scanned by a dual-source CT scanner (SOMATON Definition Flash, Siemens Healthcare) at two photon energies: 80 kVp and 140 kVp with nine different tube current settings ranging from 12 to 74 mAs for 140 kVp, and then reconstructed by soft-tissue reconstruction kernel (B30f). The DE-CTC images were subjected to a low-dose DE-EC scheme. First, our image-space DE-CTC denoising filter was applied for reduction of image noise. Then, the noise-reduced images were processed by a virtual lumen tagging method for reduction of partial volume effect and tagging inhomogeneity. The results were compared with the registered CTC images of native phantom without fillings. Preliminary results showed that our low-dose DE-EC scheme achieved the cleansing ratios, defined by the proportion of the cleansed voxels in the tagging mask, between 93.18% (12 mAs) and 96.62% (74 mAs). Also, the soft-tissue preservation ratios, defined by the proportion of the persevered voxels in the soft-tissue mask, were maintained in the range between 94.67% and 96.41%.
Year
DOI
Venue
2013
10.1117/12.2008115
Proceedings of SPIE
Keywords
Field
DocType
Computer-aided diagnosis,x-ray and CT,abdominal,CT colonography,dual-energy CT,electronic cleansing,denoising
Voxel,Nuclear medicine,Imaging phantom,Artificial intelligence,Iohexol,Virtual colonoscopy,Computer vision,Iodinated Contrast Agent,Image noise,Medical physics,Scanner,Partial volume,Physics
Conference
Volume
ISSN
Citations 
8670
0277-786X
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Wenli Cai111816.57
Da Zhang210.70
June-Goo Lee3143.52
Hiroyuki Yoshida45013.16