Title
Analysis of left atrial respiratory and cardiac motion for cardiac ablation therapy
Abstract
Cardiac ablation therapy is often guided by models built from preoperative computed tomography (CT) or magnetic resonance imaging (MRI) scans. One of the challenges in guiding a procedure from a preoperative model is properly synching the preoperative models with cardiac and respiratory motion through computational motion models. In this paper, we describe a methodology for evaluating cardiac and respiratory motion in the left atrium and pulmonary veins of a beating canine heart. Cardiac catheters were used to place metal clips within and near the pulmonary veins and left atrial appendage under fluoroscopic and ultrasound guidance and a contrast-enhanced, 64-slice multidetector CT scan was collected with the clips in place. Each clip was segmented from the CT scan at each of the five phases of the cardiac cycle at both end-inspiration and end-expiration. The centroid of each segmented clip was computed and used to evaluate both cardiac and respiratory motion of the left atrium. A total of three canine studies were completed, with 4 clips analyzed in the first study, 5 clips in the second study, and 2 clips in the third study. Mean respiratory displacement was 0.2 +/- 1.8 mm in the medial/lateral direction, 4.7 +/- 4.4 mm in the anterior/posterior direction (moving anterior on inspiration), and 9.0 +/- 5.0 mm superior/inferior (moving inferior with inspiration). At end inspiration, the mean left atrial cardiac motion at the clip locations was 1.5 +/- 1.3 mm in the medial/lateral direction, and 2.1 +/- 2.0 mm in the anterior/posterior and 1.3 +/- 1.2 mm superior/inferior directions. At end expiration, the mean left atrial cardiac motion at the clip locations was 2.0 +/- 1.5 mm in the medial/lateral direction, 3.0 +/- 1.8 mm in the anterior/posterior direction, and 1.5 +/- 1.5 mm in the superior/inferior directions.
Year
DOI
Venue
2015
10.1117/12.2081209
Proceedings of SPIE
Keywords
Field
DocType
computed tomography,ultrasonography,heart,metals,magnetic resonance imaging
Nuclear medicine,Computer vision,Artificial intelligence,Cardiac Catheters,Respiratory system,Cardiac cycle,Cardiac motion,Medicine,Cardiac Ablation,CLIPS,Magnetic resonance imaging,Ultrasound
Conference
Volume
ISSN
Citations 
9415
0277-786X
0
PageRank 
References 
Authors
0.34
1
6
Name
Order
Citations
PageRank
Maryam E. Rettmann138246.20
David R Holmes24220.31
S. B. Johnson301.01
Helko Lehmann4899.62
Richard A. Robb5645238.12
Douglas L. Packer646.03