Title
CAD system for lung cancer based on low-dose single-slice CT image
Abstract
We have been developed a computer-aided diagnosis (CAD) system for the lung cancer detection of early stage from low dose single-slice computed tomography (CT) with 10 mm beam width on chest screening. The objective of this study is to solve three problems of the conventional CAD system; (1) lesion which overlaps blood vessel, (2) lesion in contact with blood vessel and (3) lesion near upper mediastinum. This paper presents a new method to solve problem-1 and problem-2. The blood vessels, which overlap lesions and others in contact with lesion, are eliminated by detecting region of interest (ROI) with accuracy. Detection method of ROIs consists of 3 processes; firstly, streak shadows elimination using linear feature detector filter, secondly, estimation of pulmonary background bias using the intensity histogram and the opening method, and finally, ROI's border detection using laplacian filter. We evaluated the new system by apply it to 155 shadows which need confirmation diagnosis. These cases were selected from clinical test from July 1997 to December 2000 in retrospective study. True positive cases of this algorithm achieved sensitivity 91.0%. The average of false positive cases,vas 0.53 per slice.
Year
DOI
Venue
2002
10.1117/12.467086
Proceedings of SPIE
Keywords
Field
DocType
CAD system,lung cancer,single-slice CT,streak shadow,opening method
Nuclear medicine,Lung cancer,CAD,Histogram,Lesion,Streak,Computer-aided diagnosis,Region of interest,Radiology,Medicine,Mediastinum
Conference
Volume
ISSN
Citations 
4684
0277-786X
4
PageRank 
References 
Authors
0.48
0
13
Name
Order
Citations
PageRank
Mitsuru Kubo18922.51
kazuhori kubota241.15
Yamada, N.3122.43
Yoshiki Kawata419254.44
Noboru Niki518866.10
Kenji Eguchi612942.78
Hironobu Ohmatsu713845.23
Ryutaro Kakinuma89724.90
Masahiro Kaneko95519.24
masahiko kusumoto104616.28
Kiyoshi Mori114710.84
hiroyuki nishiyama124611.62
Noriyuki Moriyama1314850.47