Paper Info
Title
A lightweight discrete biphasic current stimulator for rodent deep brain stimulation
Abstract
This paper presents a miniaturized discrete system for long-term biphasic deep brain stimulation (DBS) with independently programmable anodic and cathodic currents and pulse widths, frequency, pulse order and interpulse interval. It features a single current source and an H-bridge for setting current direction. The single source allows good charge balance, limiting DC current to under 50 nA which is further reduced to below 1 nA by electrode shorting. Voltage compliance is limited to 12 V. The device along with battery power supply weighs 2.3 g. The system is highly customizable, permitting tradeoff between voltage compliance and the range, resolution and accuracy of currents and between power consumption and temporal resolution with minimal hardware modification. Based on average current consumption and nominal battery capacity, the stimulator can provide 300 μA, 130 Hz, 100 μs symmetric biphasic stimulation with an 11.5 V compliance for 14 days. Design details, characterization measurements and experimental data comparing the stimulator to a benchtop device in an anesthetized rat are presented.
Year
DOI
Venue
2015
10.1109/BioCAS.2015.7348360
2015 IEEE Biomedical Circuits and Systems Conference (BioCAS)
Keywords
Field
DocType
anesthetized rat,electrode shorting,long-term biphasic deep brain stimulation,miniaturized discrete system,rodent deep brain stimulation,lightweight discrete biphasic current stimulator,current 50 nA,voltage 12 V,mass 2.3 g,current 300 muA,frequency 130 Hz,time 100 mus,voltage 11.5 V,time 14 day
Current source,Computer science,Voltage,Anode,Pulse (signal processing),Electronic engineering,Battery (electricity),Temporal resolution,Electrical engineering,Electrode,Discrete system
Conference
ISSN
Citations 
PageRank 
2163-4025
0
0.34
References 
Authors
0
4
Name
Order
Citations
PageRank
Adan I. Acosta100.34
Muhammad S. Noor220.85
Zelma H T Kiss331.91
Kartikeya Murari414518.78