Title
Multi-test cervical cancer diagnosis with missing data estimation
Abstract
Cervical cancer is a leading most common type of cancer for women worldwide. Existing screening programs for cervical cancer suffer from low sensitivity. Using images of the cervix (cervigrams) as an aid in detecting pre-cancerous changes to the cervix has good potential to improve sensitivity and help reduce the number of cervical cancer cases. In this paper, we present a method that utilizes multi-modality information extracted from multiple tests of a patient's visit to classify the patient visit to be either low-risk or high-risk. Our algorithm integrates image features and text features to make a diagnosis. We also present two strategies to estimate the missing values in text features: Image Classifier Supervised Mean Imputation (ICSMI) and Image Classifier Supervised Linear Interpolation (ICSLI). We evaluate our method on a large medical dataset and compare it with several alternative approaches. The results show that the proposed method with ICSLI strategy achieves the best result of 83.03% specificity and 76.36% sensitivity. When higher specificity is desired, our method can achieve 90% specificity with 62.12% sensitivity.
Year
DOI
Venue
2015
10.1117/12.2080871
Proceedings of SPIE
Keywords
Field
DocType
Cervical dysplasia,automated screening,disease classification,missing data estimation
Data mining,Artificial intelligence,Missing data,Linear interpolation,Image classifier,Computer vision,Cervical cancer,Pattern recognition,Feature (computer vision),Cervix,Imputation (statistics),Cancer,Physics
Conference
Volume
ISSN
Citations 
9414
0277-786X
1
PageRank 
References 
Authors
0.41
6
5
Name
Order
Citations
PageRank
Tao Xu118711.21
Xiaolei Huang2108463.94
Edward Kim310410.48
L. Rodney Long453456.98
Sameer Antani51402134.03