Paper Info
Title
Towards enabling ultrasound guidance in cervical cancer high-dose-rate brachytherapy
Abstract
MRI and Computed Tomography (CT) are used in image-based solutions for guiding High Dose Rate (HDR) brachytherapy treatment of cervical cancer. MRI is costly and CT exposes the patients to ionizing radiation. Ultrasound, on the other hand, is affordable and safe. The long-term goal of our work is to enable the use of multiparametric ultrasound imaging in image-guided HDR for cervical cancer. In this paper, we report the development of enabling technology for ultrasound guidance and tissue typing. We report a system to obtain the 3D freehand transabdominal ultrasound RF signals and B-mode images of the uterus, and a method for registration of ultrasound to MRI. MRI and 3D ultrasound images of the female pelvis were registered by contouring the uterus in the two modalities, creating a surface model, followed by rigid and B-spline deformable registration. The resulting transformation was used to map the location of the tumor from the T2-weighted MRI to ultrasound images and to determine cancerous and normal areas in ultrasound. B-mode images show a contrast for cancer vs. normal tissue. Our study shows the potential and the challenges of ultrasound imaging in guiding cervical cancer treatments.
Year
DOI
Venue
2014
10.1117/12.2044235
Proceedings of SPIE
Keywords
Field
DocType
Ultrasound,registration,MRI,radiation therapy,cervical cancer
Brachytherapy,Artificial intelligence,Contouring,3D ultrasound,Cervical cancer,High-Dose Rate Brachytherapy,Computer vision,Medical physics,Radiology,Cancer,Magnetic resonance imaging,Physics,Ultrasound
Conference
Volume
ISSN
Citations 
9036
0277-786X
0
PageRank 
References 
Authors
0.34
5
8
Name
Order
Citations
PageRank
adrian wong100.34
samira sojoudi2133.48
marc gaudet300.34
wan wan yap400.34
Silvia D Chang5347.23
Purang Abolmaesumi6951111.52
christina aquinoparsons700.34
Mehdi Moradi821931.03