Name
Abstract | ||
|---|---|---|
We report an agglutination-based immunosensor for the quantification of C-reactive protein (CRP). The developed immunoassay sensor requires approximately 15 minutes of assay time per sample and provides a sensitivity of 0.5 mg/L. We have measured the capacitance of interdigitated electrodes (IDEs) and quantified the concentration of added analyte. The proposed method is a label free detection method and hence provides rapid measurement preferable in diagnostics. We have so far been able to quantify the concentration to as low as 0.5 mg/L and as high as 10 mg/L. By quantifying CRP in serum, we can assess whether patients are prone to cardiac diseases and monitor the risk associated with such diseases. The sensor is a simple low cost structure and it can be a promising device for rapid and sensitive detection of disease markers at the point-of-care stage. |
Year | DOI | Venue |
|---|---|---|
2015 | 10.1109/MWSCAS.2015.7282094 | 2015 IEEE 58th International Midwest Symposium on Circuits and Systems (MWSCAS) |
Keywords | Field | DocType |
interdigitated electrodes,immunoassay sensor,CRP quantification,agglutination,biosensor,capacitive sensor,cardiac marker | Capacitance,Agglutination (biology),Computer science,Capacitive sensing,Electronic engineering,Immunoassay,C-reactive protein,Analyte,Biosensor,Disease markers | Conference |
ISSN | Citations | PageRank |
1548-3746 | 0 | 0.34 |
References | Authors | |
1 | 5 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Christos Sapsanis | 1 | 26 | 3.35 |
| Shilpa Sivashankar | 2 | 0 | 1.69 |
| Hesham Omran | 3 | 28 | 6.37 |
| Ulrich Buttner | 4 | 5 | 3.39 |
| Khaled N. Salama | 5 | 345 | 46.11 |